GenomeComb

GenomeComb


Select genome comparison and filter setting

We have used GenomeComb to compare within-platform replicates (monozygotic twin genomes, Complete Genomics technology), and cross-platform replicates (Yoruban NA19240 sequenced using Illumina GAII and Complete Genomics). Extensive filter combinations were tested on these genome comparisons, and for each filter combination several metrics are reported:


Usage:

Here you can choose which genomes to compare (i.e twins or NA19240), which which coverage stringency should be used (i.e. relaxed setting or minimal coverage depth of 10 versus stringent setting or minimak coverage depth of 20). After selecting the genomes to compare different filters can be applied manually, or certain predefined settings can be used.

To browse these results, first select which genomes you want to compare:

Complete Genomics Twin Genomes
 
 
 
Low coverage depth cutoff 20
Low coverage depth cutoff 10
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Yoruban NA19240 CG/Illumina GAII
 
Illumina SNV filtering versus the Complete Genomics (CG) genome
 
Low coverage depth cutoff 20
No filtering on CG
Stringent filtering on CG
 
Low coverage depth cutoff 10
No filtering on CG
Stringent filtering on CG
 
CG SNV filtering versus the Illumina (ILL) genome
 
Low coverage depth cutoff 20
No filtering on CG
Stringent filtering on CG
 
Low coverage depth cutoff 10
No filtering on CG
Stringent filtering on CG